Impact of Glucose Variability on Dynamic Cognitive Function in Youth with T1D

Optimize a smartphone application to test dynamic cognition in youth.
A new smartphone app with excellent validity and reliability for assessing dynamic cognitive processes in adults was developed by team member Dr. Hassenstab. We will conduct a pilot study in the lab to optimize the tasks’ instructions, stimuli, and timing parameters for children and adolescents.
Optimize an analysis protocol for integrating real-time glucose fluctuations and assessments of cognition in youth with T1D.
We will collect real-time glucose level readings using continuous glucose monitoring (CGM) technology and cognitive function via the new app from youth with T1D in their daily lives. We will optimize sophisticated multivariate time-series analyses and machine learning models to integrate the data and explore the relationship between real-time glucose fluctuations and dynamic cognitive function.